Levaquin i.e. Elimination occurs mainly via excretion of unmetabolized drug in the urine. Levofloxacin may be used in children 6 months of age and older to prevent anthrax infection after possible exposure, and to treat plague infection. [PubMed Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes.Mayo Clinic does not endorse companies or products. Similar results have been reported when levofloxacin is taken with iron supplements and multi-vitamins containing zinc.A 2011 review examining musculoskeletal complications of fluoroquinolones proposed guidelines with respect to administration to athletes, that called for avoiding all use of fluoroquinolone antibiotics if possible, and if they are used: ensure there is informed consent about the musculoskeletal risks, and inform coaching staff; do not use any corticosteroids if fluoroquinolones are used; consider Adverse effects are typically mild to moderate. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.Using this medicine with any of the following medicines is not recommended. Peak serum concentrations of levofloxacin may be reduced by 90% or more, which can prevent the levofloxacin from working. 1997;25:302-6. The use of other medications in this class appear to be safe while breastfeeding; however, the safety of levofloxacin is unclear. Nov 1, 2012 Pharmacokinetics of three newer quinolones in pregnant and lactating women. Therapeutics and Clinical Risk Management 2008, 4, 843-853.) Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.The presence of other medical problems may affect the use of this medicine. No teratogenicity was seen in rabbits treated during organogenesis with oral doses up to 50 mg/kg/day (1.1 times the MRHD based on doses normalized for total BSA); maternal toxicity at that dose consisted of lower weight gain and decreased food intake compared to controls and abortion in 4 of 16 dams. Traces of levofloxacin were still detectable in breastmilk 65 hours after the dose. Saudi Pharmaceutical Journal 2011, 19, 85-93.McGregor, J. C.; Allen, G. P.; Bearden, D. T. Levofloxacin in the treatment of complicated urinary tract infections and acute pyelonephritis. The effects of a fluoroquinolone on the growth and development of infants. Make sure you tell your doctor if you have any other medical problems, especially:Portions of this document last updated: Sept. 01, 2020Copyright © 2020 IBM Watson Health. Geriatric . This medicine is not recommended for use in case of a common cold, flu, or other viral infections since it is active against infections caused by bacteria only. Antibiotics Might Lower Effectiveness of Birth Control Pill One woman was given levofloxacin 500 mg daily intravenously for 9 days, then orally for 17 days. Pharmacotherapy. Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of levofloxacin in the elderly. It trespasses in tiny amounts into breast milk. All rights reserved. Ofloxacin is a fluoroquinolone antibiotic used to treat bacterial infections such as pneumonia, bronchitis, staph infections, STDs (gonorrhea, chlamydia), urinary tract infections (UTIs), and prostate infections caused by E. coli. Other fluoroquinolone antibiotics include levofloxacin (), ciprofloxacin (), gatifloxacin (), norfloxacin (), moxifloxacin (), and trovafloxacin (). Talk to your doctor if you breastfeed your child. In addition, some medicines, especially antibiotics while breastfeeding are harmful to health and slows down baby’s development. Eur J Pediatr. During treatment with levofloxacin, the symptoms of diseases diminished significantly, but the patient complained of generalized weakness. Levofloxacin 500 MG Tablet is a broad-spectrum antibiotic used to treat a variety of conditions such as bronchitis, pneumonia, infections of the bladder, etc. In these cases, your doctor may want to change the dose, or other precautions may be necessary. However, severe, disabling, and potentially irreversible adverse effects sometimes occur, and for this reason use it is recommended that use of fluoroquinolones be limited. Tendon damage may occur during or after treatment with this ... levofloxacin 500 mg tablet. By May 2014, all but 363 cases had been settled or adjudicated.InChI=1S/C18H20FN3O4/c1-10-9-26-17-14-11(16(23)12(18(24)25)8-22(10)14)7-13(19)15(17)21-5-3-20(2)4-6-21/h7-8,10H,3-6,9H2,1-2H3,(H,24,25)/t10-/m0/s1Mouzam, M. I.; Dehghan, M. H. G.; Asif, S.; Sahuji, T.; Chudiwal, P. 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