When patients demonstrate severe AAS before surgery, it may be prudent to use fluoroscopy to guide the head positioning and intubation, under preparation for the use of a cervical collar and an awake intubation.In summary, this study showed that protrusion position using a flat pillow and a donut-shaped pillow during general anesthesia reduced ADI and increased PADI in eight RA patients with AAS. This can lead to atlanto-axial instability in about 25% of patients suffering from RA. It leads to earlier symptoms of nerve compression. 2002 May;60(5):559-66. doi: 10.1053/joms.2002.31856.Clin Rheumatol. This study investigated head position during general anesthesia for the patients with RA and proven atlantoaxial subluxation. Our conclusions may thus not apply to patients with severe subluxation, patients with vertical subluxation, or patients with preexisting neurologic symptoms. SeeClarithromycin BiDil. Felix N Fombon, FRCA, Jonathan P Thompson, BSc MD FRCA, Anaesthesia for the adult patient with rheumatoid arthritis, Rheumatoid arthritis affects 1–2% of the UK population; it is a chronic systemic inflammatory disorder.A thorough preoperative assessment including history and physical examination is essential to assess the extent and severity of the disease.Airway and neck assessment is crucial; atlanto-axial subluxation may be present and there is a potential risk of spinal cord damage.Awake fibreoptic intubation may be required for airway management.Regional anaesthesia should always be considered as an alternative to general anaesthesia.Hippocrates mentioned joint ailments in his medical treatises around 400 yr B.C. Orthopaedic interven- tion (e.g. A study conducted at the Johns Hopkins Arthritis Center found that gum disease and tooth loss are more prevalent in people who have rheumatoid arthritis (RA). Search for other works by this author on: It is a multi-system disease that may affect the function of other joints and organs in the body. Environmental factors also seem to play a role, including as yet unidentified viral or bacterial agents. Renal function should be monitored carefully in view of the possibility of pre-existing impairment, the effects of medication and perioperative fluid shifts.We are grateful to Dr James Francis, Consultant Rheumatologist, University Hospitals of Leicester for his helpful comments on this manuscript.Oxford University Press is a department of the University of Oxford. Updated consensus statement on biological agents for the treatment of rheumatoid arthritis and other immune mediated inflammatory diseasesCricoarytenoid arthritis: a cause of acute upper airway obstruction in rheumatoid arthritisCricoarytenoid rheumatoid arthritis: an important consideration in aggressive lesions of the larynxThe role of preoperative cervical spine X-rays in rheumatoid arthritisRegional anaesthesia in the anticoagulated patient: defining the risks. Importantly, RA is is a systemic disease, affecting the skeletal system as well as the cardiac and pulmonary systems and often leading to a vasculitis. J Bone Joint Surg Am 1979; 61:1003–10Hino H, Abumi K, Kanayama M, Kaneda K: Dynamic motion analysis of normal and unstable cervical spines using cineradiography: An Ordway NR, Seymour RJ, Donelson RG, Hojnowski LS, Edwards WT: Cervical flexion, extension, protrusion, and retraction: A radiographic segmental analysis. They were, on average, 58 yr old (range, 43–67 yr) with an 18-yr history of RA (4–29 yr). Anaesthesia and rheumatoid arthritis. ADI averaged 2.8 mm less when the patients were positioned on a flat pillow combined with a donut-shaped pillow than when they were positioned on a flat pillow alone. Cricoarytenoid inflammation may occur, necessitating tracheostomy.The use of patient-controlled analgesia systems may be impossible in severe rheumatic hand disease; in such cases an alternative analgesia strategy is required. There is a 13 mm dislocation between the dens and the main body of the axis. Preoperative Considerations. Anaesthesia 1993; 48:989–97Weissman BN, Aliabadi P, Weinfeld MS, Thomas WH, Sosman JL: Prognostic features of atlantoaxial subluxation in rheumatoid arthritis patients. Joint Bone Spine 2002; 69:141–54Pellicci PM, Ranawat CS, Tsairis P, Bryan WJ: A prospective study of the progression of rheumatoid arthritis of the cervical spine. 1. 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